Both Women's Health May 2013 issue & Shape April 2013 issue referenced reports on the increasing drug reactions to Grapefruit....
from Women's Health: Here's something to know before you eat a grapefruit: According to a recent study in the Canadian Medical Association Journal, a group of chemicals in the tangy fruit--called furanocoumarins--can prevent certain medications from being broken down in the body. Too much can increase the potency of some drugs by 330 percent and may cause acute kidney failure, cardiac arrest, or even sudden death (yikes!). Currently, 85 meds are known to interact badly with as little as seven ounces of juice or one grapefruit a day--including some that treat cancer, infections, and cardiovascular and psychiatric disorders--so ask your doc or pharmacist if this citrus is off-limits.
Shape cited the same report and went on to list some of the drugs ...there are now 85 known medications to watch out for, including common ones like the antidepressant sertraline (Zoloft) and the cholesterol med simvastatin (Zocor). "Grapefruit, as well as Seville oranges and pomelos, contains chemicals that interfere with our ability to break down these drugs before they hit your bloodstream, so you could end up with a much higher dose than prescribed," warns David Bailey, Ph.D., a clinical pharmacologist at the Lawson Health Research Institute in Canada.
from Women's Health: Here's something to know before you eat a grapefruit: According to a recent study in the Canadian Medical Association Journal, a group of chemicals in the tangy fruit--called furanocoumarins--can prevent certain medications from being broken down in the body. Too much can increase the potency of some drugs by 330 percent and may cause acute kidney failure, cardiac arrest, or even sudden death (yikes!). Currently, 85 meds are known to interact badly with as little as seven ounces of juice or one grapefruit a day--including some that treat cancer, infections, and cardiovascular and psychiatric disorders--so ask your doc or pharmacist if this citrus is off-limits.
Shape cited the same report and went on to list some of the drugs ...there are now 85 known medications to watch out for, including common ones like the antidepressant sertraline (Zoloft) and the cholesterol med simvastatin (Zocor). "Grapefruit, as well as Seville oranges and pomelos, contains chemicals that interfere with our ability to break down these drugs before they hit your bloodstream, so you could end up with a much higher dose than prescribed," warns David Bailey, Ph.D., a clinical pharmacologist at the Lawson Health Research Institute in Canada.
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